HDAC6 inhibitor NCT-14b

CAS No.

HDAC6 inhibitor NCT-14b ( NCT-14b )

Catalog No. M17048 CAS No.

A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    HDAC6 inhibitor NCT-14b
  • Note
    Research use only, not for human use.
  • Brief Description
    A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
  • Description
    A potent, selective HDAC6 inhibitor with IC50 of 84 nM, with IC50s of >3.5 uM for the other HDAC isoforms.
  • Synonyms
    NCT-14b
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    --
  • Formula Weight
    465.69
  • Molecular Formula
    C26H43NO4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ——
  • Chemical Name
    (S)-S-7-(adamant-1-ylamino)-6-(tert-butoxycarbonyl)-7-oxoheptyl-2-methylpropanethioate

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Matsuba S, et al. J Pharmacol Exp Ther. 2014 Dec;351(3):510-8.
2. Itoh Y, et al. J Med Chem. 2007 Nov 1;50(22):5425-38.
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